Complete Male Connectome · 166,700 Neurons · 125M Synapses
The Whole Fruit Fly Brain,
Running In-Silico in Your Browser.
A unified suite of client-side neuro-computational engines built from Google Research and HHMI Janelia's landmark connectomics milestone. Zero servers, zero build steps, and zero dependencies.
166,700
Neurons Mapped
125,000,000+
Synapses Traced
11,779
Identified Cell Types
60 FPS
Live WebGL Engine
0 MB
Backend Overhead
Full EM Reconstruction
MUSCA
Complete 3D wiring diagram with forward spike propagation and reverse behavior-to-circuit graph search.
- Atlas Mode: Search 11,779 cell types; color by transmitter, hemisphere, or sex dimorphism.
- Poke Mode: Forward decaying spike wave across the real 2.8M-edge matrix.
- Reverse Search: Work backwards from 9 verified behaviors to the exact sensory-motor circuits.
- Lesion Sandbox: Target and ablate individual neurons or pathways.
166,700Neurons
2.82MEdges
1.1MSynapse Points
Launch MUSCA Connectome →
Spiking Neural Dynamics
166k
Live-grown procedural LIF spiking neural network running with axonal delays and Hebbian aversive conditioning.
- LIF Electrophysiology: Real-time leaky integrate-and-fire simulation with 4:1 E/I balance.
- Sensory-Motor Cascades: Odor delivery triggering Antennal Lobe → Mushroom Body → Lateral Horn.
- Aversive Conditioning: Pair odor with PPL1 dopamine shock to shift behavioral valence.
- Ablation Proof: Silencing Mushroom Body completely blocks synaptic plasticity.
166,000Neurons
2.30MSynapses
60 FPSWebGL Blended
Launch 166k Spiking Engine →
3D Neuropil Circuit
SYNAPTICA
Playable 3D neuropil circuit with visual/olfactory pathways and interactive Mushroom Body memory training.
- Neuropil Topology: Optic Lobes, Antennal Lobes, Mushroom Body, Central Complex, VNC.
- Sensory Injection: Flash Eyes (visual-motor cascade) & Puff Odor (olfactory cascade).
- Train Memory: Repeated cue firing strengthens Kenyon Cell → MBON connections in real time.
- Ambient Mode: Autonomous living neural activity display for cinematic visualization.
12Neuropils
Live HUDSynapse Counter
HebbianMemory Gauge
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Sparse Reinforcement Learning
FlyGambit
Sparse connectome-constrained artificial brain learning chess live with real-time neuropil lesioning experiments.
- Live Learning: REINFORCE + learned value baseline running client-side with zero dependencies.
- Synaptic Pulse: 3D fluorescence specimen pulsing real activations per piece move.
- Lesion Sandbox: Silence Optic, Lobula, Mushroom Body, or Central Complex mid-game.
- Procedural Sound: Web Audio synthesized synaptic clicks, capture thuds, and checkmate chords.
~1,200Neurons
~28,000Synapses
ZeroDependencies
Launch FlyGambit Chess →
Genetic Locomotion Evolution
FlySprint
Evolved 6-legged biomechanical gait controllers competing live across 100m–400m dashes and 10-barrier hurdles.
- Genetic Evolution: Evolve 94-weight central pattern generators from scratch in your browser tab.
- 4 Track Events: 100m sprint, 200m dash, 400m endurance pacing, and 100m hurdle barrier jumping.
- Fluorescent Athletes: GFP, Scarlet, Yellow, Brown, and Turquoise competing on a 3D stadium track.
- Director Camera: Dynamic cinema camera tracking runners with photo-finish flash and crowd audio.
1–5Athletes
94Weights/Fly
1,000+Gens/Min
Launch FlySprint Racing →
Sensory Electrophysiology
FLYMIND
Interactive connectome playground: poke real sensory cascades, explore 42 neuron classes, train mushroom body, and synthesize courtship song.
- Poke the Fly: Stimulate smell, vision, touch; watch Or42b, Or56a, and Giant Fiber fire.
- Connectome Explorer: Force-directed graph of 42 classes with BFS shortest-path tracer.
- Train the Fly: Playable Mushroom Body with dopaminergic KC→MBON depression.
- Courtship Song Lab: Procedural ~200 Hz pulse song synthesis with female acoustic response.
42Neuron Classes
642Synapses
ZeroRuntime Deps
Launch FLYMIND Playground →
Connectome Football
FLYKICK
Two teams of 5 neural-circuit flies play football with real-time Brain Cam streaming and manual possession override.
- Neural Athletes: 10 flies driven by 11-neuron circuits (R1-R6, T4/T5, CX, Kenyon, Motors).
- Possession Hijack: Click any fly to seize Central Complex steering with WASD & charge-kick.
- Brain Cam Telemetry: Live electrophysiology trace showing sensory spikes and motor bursts.
- Procedural Stadium: Dynamic crowd roar, referee whistles, wall bounces, and goal beams.
2 Teams5v5 Football
11Neurons/Fly
Brain CamLive Telemetry
Launch FLYKICK Football →
Counterfactual Twin
CHRONOFLY
Deterministic counterfactual neural twin lab: observe divergence between control and intervened circuits under identical inputs.
- Twin Circuits: Identical recurrent networks with shared random seed.
- Intervention Axis: Silence, stimulate, or modulate one twin; track real‑time divergence.
- Full Reproducibility: Seed‑deterministic; every experiment is repeatable.
- Educational: Synthetic LIF dynamics; no biological data claimed.
2Twin Circuits
1Intervention Axis
FullReproducibility
Launch CHRONOFLY →
Sleep‑Replay
ONEIRO
Sleep‑replay and maze‑learning observatory: hippocampal sharp‑wave ripples coupled with cortical Hebbian learning.
- SWR Events: Detected when hippocampal population activity exceeds threshold.
- Hebbian Learning: Cortical weight potentiation during replay intervals.
- Deterministic: Fully reseeding; same seed = same maze walk, SWR & weight evolution.
- Educational: Synthetic place‑field model; no biological data claimed.
1Maze Trajectory
1Sleep Interval
HebbianLearning Rule
Launch ONEIRO →
The Connectome Architecture
The complete central nervous system of Drosophila melanogaster comprises the central brain (processing vision, olfaction, navigation, and associative memory) connected to the ventral nerve cord (VNC) via descending neurons (DNs). Each simulator in this suite demonstrates how micro-scale synaptic connectivity translates directly into macro-scale behavioral output.
[ SENSORY PERCEPTION ]
• Photons & Optical Flow ──► Optic Lobes (Lamina → Medulla → Lobula → LPTCs)
• Odorants & Pheromones ──► Antennal Lobes (Glomeruli) → Mushroom Body (Kenyon Cells)
• Acoustic Vibrations ──► Johnston's Organ (JO-A1) → Antennal Mechanosensory Center (AMMC)
│
▼
[ CENTRAL INTEGRATION & MEMORY ]
• Heading Navigation ──► Central Complex (Ellipsoid Body Ring Attractor)
• Associative Learning ──► Mushroom Body Output Neurons (MBONs) + Dopamine (PPL1 / PAM)
• Courtship & Mate Choice ──► P1 Courtship Hub (Male-Specific Fru+/Dsx+ Clusters)
│
▼
[ MOTOR COMMAND (DESCENDING PATHWAYS) ]
• Giant Fiber Takeoff ──► DNp01 (Escape Jump Command)
• Courtship Sing Back ──► DNp02 (Unilateral Wing Extension)
• Steering Modulation ──► DNp31 (Flight Motor Coordination)
│
▼
[ VENTRAL NERVE CORD & EFFECTORS ]
• T1 Neuromeres ──► Forelegs (Grooming & Substrate Sensing)
• T2 Neuromeres ──► Flight & Wing Vibration (Pulse & Sine Song)
• T3 Neuromeres ──► Tergal Trochanter Jump Muscles (TTMn)
Scientific Citation:
Google Research, Howard Hughes Medical Institute (HHMI Janelia), and the FlyEM Consortium.
"Sexual dimorphism in the complete connectome of the Drosophila male central nervous system",
Cell (September 2026).
Read the official announcement:
Google Research Connectomics Milestone